The FilmArray® meningitis/encephalitis (ME) panel is a multiplex PCR assay which can detect the most commonly identified pathogens in central nervous system infections. Case study 1: a toddler with mild meningitis. Meningitis Shafaat Ullah BSN. • It can occur as a complication of other disease and 50% is an opportunistic infection. Bacterial Infection and Immunity. The inflammation is usually caused by an infection of the fluid surrounding the brain and spinal cord. Bacterial Meningitis. Laboratory Diagnosis, Prevention and Treatment of Bacte rial Infection. JUBELENE GUMULON, ALEXIS NICOLE UPPAL, GAGAN DEEP RICAFRENTE, DHARLEEN SALINAS, NICA SUNER, KERBY JANE TERENCIO, MAJELLA BACTERIAL MENINGITIS • Most common form of meningitis. Cryptococcus neoformans var. • Meninges : membran yang mengelilingi otak dan sumsum tulang belakang. Infection may occur either through the blood (blood borne) or by direct spread along sinuses and veins from other parts of the body. Through the use of experimental animal models of infection, a great deal of information has been gleaned concerning the pathogen … enteroviruses are the most common viral cause. • Of newborns, 20-30% may die from bacterial meningitis. It is a life-threatening medical emergency. Case Study • A 3 yr old girl was brought to the emergency room by her parents because of fever and loss of appetite for the past 24 hrs and difficulty in arousing her for the past 2 hrs. DOMINGO, ABIGAIL EVANGELISTA, DEITHER FELICIANO. All untreated cases of cryptococcal meningitis are ultimately fatal. Microbiology of Acute Pyogenic Meningitis - Definition Pyogenic meningitis is an inflammation of the meninges affecting Pia, Arachnoid and subarachnoid space. Urinary Tract Infections (UTI) Lab investigations of PUO. Recommendations are based on the current evidence from literature and incorporate NICE Bacterial Meningitis and Meningococcal Septicaemia Guideline CG102. It may be caused by viruses, bacteria, fungi and protozoa. INTRODUCTION. Related Journals of Meningits Clinical presentation. From its original recognition in 1805 until the early 1900s, bacterial meningitis due to Haemophilus influenzae and Streptococcus pneumoniae was virtually 100 percent fatal. Meningococcal meningitis is the term used to describe a bacterial form of meningitis caused by Neisseria meningitidis. INTRODUCTION. 4. Neisseria meningitidis, an exclusive pathogen of humans, remains the leading worldwide cause of meningitis and fatal sepsis, usually in otherwise healthy individuals. Meningitis can be . 32 Full PDFs related to this paper. Mycobacterium tuberculosis, which causes tuberculosis or TB, is a less common cause of bacterial meningitis (called TB meningitis). Microbiology of Acute Pyogenic Meningitis. The most common symptoms are fever, headache, and neck stiffness. Gen Khyber Medical University 4/3/2017 1 2. Mutah University. The PowerPoint PPT presentation: "Microbiology of Acute Pyogenic . The list of pathogens which can potentially cause meningitis, encephalitis, and meningoencephalitis is broad. Infection of the meninges, brain and spinal cord results in meningitis, encephalitis, brain abscess and . Study Resources. Neisseria meningitidis (the meningococcus) causes significant morbidity and mortality in children and young adults worldwide through epidemic or sporadic meningitis and/or septicemia. • In 2010 - 420, 000 deaths • In 2013 - 303,000 deaths. Physical examination showed Kernig's and Brudzinski's . However, in part, reports of both false positive and false negative detections have resulted in concerns about adoption. . Tuberculous Meningitis (TBM) is a form of meningitis characterized by inflammation of the membranes (meninges) around the brain or spinal cord and caused by a specific bacterium known as Mycobacterium tuberculosis. DOMINGO, ABIGAIL EVANGELISTA, DEITHER FELICIANO. Canavanine-glycine-bromothymol blue (CGB) medium is used to identify Cryptococcus isolates. there may be variations in clinical presentation. Bacterial meningitis. BACTERIAL MENINGITIS. Meningitis is acute or chronic inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges. MENINGITIS Farmakoterapi Infeksi dan Malignansi fPENDAHULUAN • Meningitis infeksi meninges. View meningitis.ppt from MEDICAL SU MCHB BSN at Moi University. Bacterial meningitis remains a disease with associated unacceptable morbidity and mortality rates despite the availability of effective bactericidal antimicrobial therapy. Microbiology-pseudomonas Ppt (1) - Free download as Powerpoint Presentation (.ppt / .pptx), PDF File (.pdf), Text File (.txt) or view presentation slides online. •Isolation & identification (Culture): In BA, CA, MA 37 0C aerobically for 24-48 hrs, cell culture for viral infections. - A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3ce18d-ZGI4N This form of meningitis is associated with high morbidity and mortality. Meningitis is an acute inflammation of the membranes (meninges) surrounding brain and spinal cord. Meningitis can be life-threatening because of the inflammation . It extends from the optic chiasm to . Avg rating:1.0/5.0. Cryptococcal meningitis: Only in a small proportion of cases, hematogenous spread results in subacute or chronic meningitis or meningoencephalitis. • Appearance • Opening pressures • Cell count and differentials • Biochemistry - proteins, glucose • Microbiology - culture, gram stain, . Through the use of experimental animal models of infection, a great deal of information has been gleaned concerning the pathogenic and pathophysiologic mechanisms . BACTERIAL MENINGITIS. N. meningitidis is a common cause of community-acquired bacterial meningitis in both children and adults. MENINGITIS PRESENTER:NYORIANA V OYUGI FACILITATOR: Dr Kiptoon September 30, Study Resources. BSN 1Y2-1. MENINGITIS Pathophysiology • The infectious agents (ie, bacteria, virus, fungus, parasite) enter the . otitis • Localised and generalised infections • Urinary tract infection after catheterization • Iatrogenic meningitis • Post tracheostomy pulmonary infections. View lab diagnosis of meningitis.ppt from BIOTECH AS101 at University of Health Sciences Lahore. 17. It is important to know whether the cause is viral or bacterial as this will determine how to treat the patient. Bacterial meningitis also produces effects on blood vessels in the subarachnoid space with resulting vasculitis, vessel narrowing, thrombosis, and ischemia or infarction of the brain. MCB2340C Section 08 General Microbiology- Module 04 Lecture Quiz.docx. View Meningitis bacterial and aseptic ..ppt from NURSING MISC at Mutah University. Bacteriophage. Through the use of experimental animal models of infection, a great deal of information has been gleaned concerning the pathogen … Viral meningitis is the most common type of meningitis. Definition of bacterial meningitis. Description. Hospital Acquired Infections. Young children often exhibit only nonspecific symptoms . ; Microbiology: A Human Perspective. It can be caused by viruses that are commonly contagious in the community, including enterovirus, mumps virus, herpes simplex virus, varicella zoster virus (which normally causes chickenpox), Epstein-Barr virus, and West Nile virus. Introduction • Bacterial meningitis is an inflammation of the leptomeninges, usually causing by bacterial infection. It is characterized by swelling, headache, fever and a stiff neck. . • 80% of all cases are acute bacterial meningitis • Can be life threatening. • Meningitis adalah infeksi yang menular. In this review, we describe the biology, microbiology, and epidemiology of this exclusive human pathogen. Meningitis is a devastating disease with a high case fatality rate and leading to serious long-term complications (sequelae). Why Study Microbiology? . Bacterial Physiology. N. meningitidis - Epidemic strains/endemic strains - "meningitis" belt in sub-Saharan Africa (type A) Sporadic cases - types B, A, W135, Gram negative (LPS) - Rapid uptake by the epithelial cells - Receptor mediated endocytosis Sepsis Encapsulated - requires IgG + complement to phagocytose Carriers in the population - increased carriage . Meningitis refers to inflammation of the leptomeninges and CSF within the subarachnoid space that exists between the pia mater and the arachnoid layers. Eva is unusually tired and is complaining that her legs are aching. This new release is divided into five sections that cover treatment strategies, imaging, molecular diagnosis, management of CNS infections with metal . Provided by: erkeMedS. In TBM, the disorder develops gradually. . Meningitis remains a major global public-health challenge. Bacterial Variation. N. meningitidis is a common cause of community-acquired bacterial meningitis in both children and adults. Related Presentations. Treatment with antibiotics and other drugs is usually effective . INTRODUCTION. Clinical manifestation of CNS infection can consist of fever, headache, vomiting, photophobia, stiff neck, and focal neurological presentations. Fungal meningitis Fungal meningitis is relatively uncommon and causes chronic meningitis. What Is Meningitis?. EL HUSSEINYS ESSENTIALS OF MICROBIOLOGY AND IMMUNOLOGY.pdf. Meningitis is a serious and potentially life-threatening disease, and involves an inflammation of the membranes that cover the brain and spinal cord, called the meninges. Bacterial meningitis is an inflammation of the meninges, in particular the arachnoid and the pia mater, associated with the invasion of bacteria into the subarachnoid space, principles known for more than 100 years [Flexner, 1907].The pathogens take advantage of the specific features of the immune system in the CNS, replicate and induce inflammation . Preparing for lumbar puncture If possible, three tubes (1 ml each) of . Introduction. Introduction: Leptomeningitis is an inflammation of the membranes surrounding the brain and spinal cord (para-arachnoid). Bacterial meningitis remains a disease with associated unacceptable morbidity and mortality rates despite the availability of effective bactericidal antimicrobial therapy. • The infection can cause the tissues around the . SURGERY 20932. Many of these bacteria can also be associated with another serious illness, sepsis. Slides: 50. Meningitis is a serious and potentially life-threatening disease, and involves an inflammation of the membranes that cover the brain and spinal cord, called the meninges. Clinical Microbiology Lecture Notes. Powerpoint links collected from the website of : Prof Sudheer Kher, Prof TV Rao & Dr. Ekta. Meningitis/Encephalitis Pathogen Panel . A serious infection ,associated with marked . Read Paper. - PowerPoint PPT presentation. Statistics According to a report published, in the United States 4,100 cases of bacterial meningitis were reported including 500 deaths occurred each year in between 2003-2007. due to the type of pathogen, patient age, host immune status. Bacterial meningitis remains a disease with associated unacceptable morbidity and mortality rates despite the availability of effective bactericidal antimicrobial therapy. Infection may occur either through the blood (blood borne) or by direct spread along sinuses and veins from other parts of the body. a papule with surrounding erythema — appears. VIRAL MENINGITIS/ENCEPHALITIS - Title: Presentazione di PowerPoint Author: Utente Last modified by: saverio Created Date: 6/8/2006 12:58:52 PM . Bacterial meningitis is a life-threatening infection of the linings or meninges of the brain and spinal cord. Infection with Neisseria meningitidis can produce a variety of clinical manifestations, ranging from transient fever and bacteremia to fulminant disease with death ensuing within hours of the onset of clinical symptoms. Typically in bacterial meningitis the white cell count is much higher than in viral meningitis (and is a different type of white cell), the protein is much higher and the glucose is much lower than in viral meningitis. Create Survey | Create Quiz | Create Lead-form Get access to 1,00,000+ PowerPoint Templates (For SlideServe Users) - Browse Now. 5. Fungal meningitis Cryptococcal meningitis is a common fungal form of the disease that affects people with immune deficiencies, such as AIDS. General Characteristic for Bacterial Meningitis. Bacterial meningitis is the infection of the arachnoid membrane, subarachnoid space, and cerebrospinal fluid by bacteria. And they're ready for you to use in your PowerPoint presentations the moment you need them. CLINICAL MANIFESTATIONS CLINICAL MANIFESTATIONS a break in the epithelium during sexual contact with an infected individual. Signs and symptoms of cryptococcal meningitis. The subarachnoid space is bounded externally by the arachnoid membrane and internally by the pia, and dips into the brain along blood vessels in the perivascular (Virchow-Robin) spaces. Eva is a three-year-old girl who is on holiday with her grandparents. In recent years, significant advances have improved our understanding of the epidemiology and genetic basis of meningococcal disease … General Discussion. Early effective therapy for both bacterial and certain viral pathogens has been associated with improved outcomes. Symptoms may be mistaken for the flu. It significantly decreases the time to diagnosis of ME and data has yielded several positive outcomes. Meningitis is mostly caused by viral infection but can also be caused by bacteria and fungi. Epidemics of meningitis are seen across the world, particularly in sub-Saharan Africa. • To avoid the potential for contamination of the material, all tubes must be delivered first to the Microbiology Laboratory. • The infection can cause the tissues around the . Bacterial Meningitis can be treated with antibiotics, but quick medical attention is extremely important. A serious infection ,associated with . Download Presentation. Bacterial Meningitis: Basic Facts. MICROBIOLOGY OF OTITIS, SINUSITIS, AND MENINGITIS • 2005-02 • diseases and their agents that afflict various parts of the head • middle ear (otitis media) • sinuses (sinusitis) • central nervous system (meningitis) • Upper respiratory tract • lack of cellular and humoral defenses • normal flora • almost all of these diseases begin with infection of the nasopharynx and/or . The inflammation is usually caused by an infection of the fluid surrounding the brain and spinal cord. In 1913, Simon Flexner's introduction of intrathecal meningococcal antiserum decreased the mortality of meningococcal meningitis from 75 to 31 percent, but the clinical outcome did not dramatically improve . Microbiology of Acute Pyogenic Meningitis - Definition Pyogenic meningitis is an inflammation of the meninges affecting Pia, . This inflammation can be caused by bacterial infections or viral infections. • Although meningitis is a notifiable disease, the exact incidence rate is unknown. •Immunological test : Detection of bacterial antigens & Ag of C.neoformans from CSF by LAT or other tests. Bacterial meningitis is an infection of the spinal cord and the cerebral fluid around the brain( cdc ). Clinical description Meningitis is the inflammation of the protective membranes covering the brain and spinal cord known as the meninges. Explanation: A spinal tap (or lumbar puncture) is the most common method of obtaining a sample for the fluid in the spinal canal to determine a diagnosis for encephalitis or meningitis. General Characteristic for Bacterial Meningitis. Molecular Microbiology: Diagnostic Principles and Practice is a textbook for molecular diagnostics courses that can also be used by anyone involved with diagnostic test selection and interpretation. - A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 68084f-MzFmM . meningitis caused by organisms other than bacteria. Patient Information: See related handout on the pneumococcal conjugate vaccine . • The developmental history had been normal since birth. It may be caused by viruses, bacteria, fungi and protozoa. Lecture 1 Bacterial meningitis Dr. Abdelraouf A. Elmanama Islamic University-Gaza Medical Technology Department Anatomy Meningies CNS infections Meningitis Infection . JUBELENE GUMULON, ALEXIS NICOLE UPPAL, GAGAN DEEP RICAFRENTE, DHARLEEN SALINAS, NICA SUNER, KERBY JANE TERENCIO, MAJELLA BACTERIAL MENINGITIS • Most common form of meningitis. Skin, Soft tissue and Mucus membrane infections. Create Presentation . fungal meningitis; 9 pages. Definition Pyogenic meningitis is an inflammation of the meninges affecting Pia, Arachnoid and subarachnoid space. MICROBIOLOGY OF OTITIS, SINUSITIS, AND MENINGITIS • 2005-02 • diseases and their agents that afflict various parts of the head • middle ear (otitis media) • sinuses (sinusitis) • central nervous system (meningitis) • Upper respiratory tract • lack of cellular and humoral defenses • normal flora • almost all of these diseases begin with infection of the nasopharynx and/or . Majority of cases caused by 2 types of bacteria. MICROBIOLOGY PPT LECTURE NOTES - set 8. Neisseria meningitidis: meningitis. 3 The exact cause of the inflammation, however, can vary. If bacterial meningitis is suspected, CSF is the best clinical specimen to use for isolation, identification, and characterization of the etiological agents. Photophobia and an altered mental status was also noted. When inoculated in this medium and incubated at room temperature for 5 days C. neoformans var neoformans forms yellow coloured colonies . Disinfection and Sterilization. Headache; Fever Clinical description Meningitis is a disease caused by the inflammation of the protective membranes covering the brain and spinal cord known as the meninges. Meningitis.ppt 1. View introduction to Microbiology.ppt from AA 1Introduction to Microbiology Microbiology: The Science Introduction What is Microbiology? • 80% of all cases are acute bacterial meningitis • Can be life threatening. Meningitis is an infection/inflammation of the brain and spinal cord surrounding membranes known as the meninges.

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